46+ Bipolar Affective Disorder Pathophysiology Pics. Bipolar disorder affects between 0.4% and 1.6% of the world's population, according to recent reports. The cause and mechanism of bipolar disorder is not yet known, and the study of its biological origins is ongoing.
With rapid cycling the patient changes from depression to manic at least 4 times.
Bipolar i disorder is a very serious mental illness, but usually it has an excellent outcome when treated. Hypothyroidism, either overt or more commonly subclinical, appears to the commonest abnormality found in bipolar disorder. The hallmark of the disorder is mood elevation (mania or hypomania). These loci are grouped as major affective disorder (mafd) loci.